NASDAQ NMS - GLOBAL MARKET · SYRE
-2.62% · -$2.43 · Vol 3.4M
Market closed · last close 4:00 PM ET · price as of 16:56:24 ET
Spyre Therapeutics Inc

Spyre Therapeutics Inc

Biotechnology
$90.25
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Veridion Score

BETAHIGH CONF · 6 of 6 factors measuredMethodology
SYRE
Spyre Therapeutics Inc
Sat Sep 19 · market closed · Markets closed · resumes Mon 9:30 ET
Upper range

Highest qualified requires a score of at least 75 and high confidence, including full factor coverage. Upper range can hold a higher score with lower confidence.

Composite intelligence score across six company factor categories. Missing inputs are excluded from the active factor subset.

71/ 100
Veridion Score
Upper range · HIGH confidence · 6 of 6 factors measured
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Confidence: HIGH · 6 of 6 factors measured · Sat Sep 19 · market closed · Markets closed · resumes Mon 9:30 ET
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About Spyre Therapeutics Inc
PHARMACEUTICAL PREPARATIONS
Listed since
2016
Employees
112
Country
US

Spyre Therapeutics Inc is a clinical-stage biotechnology company pioneering long-acting antibodies and antibody combinations to redefine the standard of care for inflammatory bowel disease (IBD) and rheumatic diseases. Spyre's pipeline includes extended half-life antibodies targeting α4β7, TL1A, and IL-23 in development as monotherapies and pair-wise combinations. It has a single reportable segment, which is the development of biopharmaceutical products for the treatment of patients with IBD and other immune-mediated disease.

Key statistics

Reported fields plus Veridion-computed history. Unsourced tiles are omitted.

Open
$92.82
Day high
$93.34
Day low
$89.85
Previous close
$92.68
52W high
$108.92
-17.14% from high
52W low
$14.88
80% of range
Market cap
$8.2B
EPS
$-1.6533
Beta
1.39
Shares out
88.2M
Volume
3.4M
2.90× rel vol
Avg volume
1.2M
VWAP
$90.47
Price history computed in-house
1W
-0.39%
1M
-16.27%
3M
+2.16%
1Y
+506.52%
YTD
+175.49%
SMA 50 $97.95 · below
SMA 200 $64.85 · above
52W position 80%

SYRE overview

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Public disclosures

Congress activity in SYRE

No receipt-qualified Congressional disclosure is present for SYRE in the cached public ledger.

Federal contracts

SYRE contract awards, year to date.

Public federal awards linked to this ticker.

Not disclosed
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Lobbying spend

SYRE lobbying filings, year to date.

Registered lobbying filings matched to Spyre Therapeutics Inc.

$60.0K
Refresh interval: 12hSource: LDA disclosure filings
Health Issues
Filing
$40.0K
SPYRE THERAPEUTICS INC.

ARNOLD & PORTER KAYE SCHOLER LLP

Apr 20, 2026
Filing
$10.0K
SPYRE THERAPEUTICS INC.

ARNOLD & PORTER KAYE SCHOLER LLP

Jul 17, 2026
Filing
$10.0K
SPYRE THERAPEUTICS INC.

ARNOLD & PORTER KAYE SCHOLER LLP

Jan 15, 2026
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